Product Overview Revolution Revolution Description Revolution for dogs and cats is an easy to use, topical treatment that kills fleas, flea eggs, ear mites, scabies and controls dog tick infestations in dogs. In addition, it helps with heartworm control as well as the spread of parasitic worms like roundworm and hookworm. This monthly solution for tick and flea prevention in dogs and cats is FDA-approved and safe to use. Applied to the base of your pet’s neck, Revolution is a quick drying, non-greasy medication that seeps into the pet’s skin to more efficiently distribute the medicine all across your pet’s body. Ingredients Revolution for dogs and cats contains Selamectin Medication GuideGuide to Revolution for Dogs and Cats (Selamectin) Product Details Side Effects and Warnings Revolution for dogs and cats is well-tolerated by pets, with less than 1% displaying symptoms. Some exhibited temporary hair loss or skin irritation at the application site. More serious symptoms may include excessive drooling, rapid breathing, lack of coordination, vomiting, or diarrhea; consult with a veterinarian immediately if these appear. SpecificationAsk your veterinarian about using Revolution for dogs and cats, or consult with one of our pet care specialists at 1-800-844-1427. This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law. Manufacturer Information Revolution is manufactured by Pfizer OptionUPC/SKUPuppies/Kittens under 5 lbs – 3 Month Supply087219034712Dogs – 5.1-10 lbs., 6 Month Supply087219034750Dogs – 10.1-20 lbs., 6 Month Supply087219034774Dogs – 20.1-40 lbs., 6 Month Supply087219034798Dogs – 40.1-85 lbs., 6 Month Supply087219034811Cats – 5-15 lbs., 6 Month Supply087219034736Dogs – 85.1-130 lbs., 3 Month Supply087219060223Dogs – 5.1-10 lbs., 12 Month Supply(unavailable)Dogs – 85.1-130 lbs., 6 Month Supply087219051214Dogs – 40.1-85 lbs., 12 Month Supply(unavailable)Dogs – 20.1-40 lbs., 12 Month Supply(unavailable)Dogs – 10.1-20 lbs., 12 Month Supply(unavailable)Dogs – 5.1-10 lbs., 3 Month Supply087219060148Dogs – 10.1-20 lbs., 3 Month Supply087219060162Dogs – 20.1-40 lbs., 3 Month Supply087219060186Dogs – 40.1-85 lbs., 3 Month Supply087219060209Cats – 5-15 lbs., 3 Month Supply087219060124Cats – 15-22 lbs., 6 Month Supply087219104279Cats – 15-22 lbs., 3 Month Supply087219104293Cats – 5- 15 lbs., 12 Month Supply(unavailable)Cats – 15-22 lbs., 12 Month Supply(unavailable)Dogs – 85.1 – 130 lbs., 12 Month Supply(unavailable) Instructions Care Instructions Store Revolution for dogs and cats at room temperature. Directions Revolution for dogs and cats is for once-monthly (preferably on the same date each month) use either year round, or only during mosquito season. To administer Revolution, part the hair between your pet’s shoulder blades and apply the contents of a tube of the proper dose to the skin. Dosage is dependant on weight; consult with a veterinarian to determine the proper amount.
Product Overview Revolution Revolution Description Revolution for dogs and cats is an easy to use, topical treatment that kills fleas, flea eggs, ear mites, scabies and controls dog tick infestations in dogs. In addition, it helps with heartworm control as well as the spread of parasitic worms like roundworm and hookworm. This monthly solution for tick and flea prevention in dogs and cats is FDA-approved and safe to use. Applied to the base of your pet’s neck, Revolution is a quick drying, non-greasy medication that seeps into the pet’s skin to more efficiently distribute the medicine all across your pet’s body. Ingredients Revolution for dogs and cats contains Selamectin Medication GuideGuide to Revolution for Dogs and Cats (Selamectin)
Revolution (selamectin) Topical Parasiticide is available as a colorless to yellow, ready to use solution in single dose tubes for topical (dermal) treatment of dogs six weeks of age and older and cats eight weeks of age and older. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. The chemical composition of selamectin is (5Z,25S)-25-cyclohexyl-4′-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-hydroxyiminoavermectin A1a.
Selamectin (trade names Revolution, Stronghold) is a topical parasiticide and anthelminthic used on dogs and cats, distributed by Zoetis, a former Pfizer subsidiary. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. It also removes 2 types of lungworm in cats (Aelurostrongylus abstrusus, Eucoleus aerophilus) and one type of lungworm in dogs (Eucoleus aerophilus). It is structurally related to ivermectin and milbemycin. Selamectin is not approved for human use.
Selamectin, the active ingredient in Revolution, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Efficacy of macrocyclic lactones decreases below 100% in dogs, however, if first administered >2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using Revolution beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at >8 weeks of age), or gaps of >2 months in the administration of Revolution during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heartworms prior to the initiation of Revolution may be harboring pre-patent infections at the time Revolution was started. Testing such animals 3–4 months after initiation of Revolution would be necessary to confirm their negative heartworm status.
Brand Name Revolution Pronunciation REV-o-LOO-shun Common Drug Name Selamectin What should I discuss with my veterinarian while considering Revolution? Talk to your veterinarian about the heartworm testing that is recommended before starting your pet on a heartworm prevention program. Some intestinal parasites, such as hookworms and roundworms can be spread to people. Talk to your veterinarian about other measures you can take to prevent your pet from being infected with intestinal worms, and protecting yourself. Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications. What should I do if I miss a dose? If a dose is missed and over 30 days have gone by since the last dose, apply Revolution immediately and resume a monthly dosing schedule. Tell your veterinarian that a dose was missed. What is the most important information I should know? If the interval between doses is longer than one month, the efficacy of the drug is reduced. Do not give this medication orally. Who should not take it? Do not use on kittens less than 8 weeks of age. Use with caution in sick, weak, or underweight animals. Safe to use on breeding animals and pregnant and nursing females. This medication should only be given to the pet for which it was prescribed. What side effects may be seen when taking Revolution? Side effects are very rare, but may includedincoordination, trembling, or drooling. If Revolution is accidently given orally, you may see drooling and vomiting. Contact your veterinarian immediately if you observe any of these signs. How is it stored? Store below 86°F. Keep out of reach of children and pets. What should I do if I know of or suspect there has been an overdose? If you know or suspect your pet has had an overdose, or if you observe weakness, staggering, dilated pupils, trembling, drooling, or pressing the head against a wall, contact your veterinarian immediately. What should I avoid when giving my pet Revolution? Although there are no known drug or food interactions with this medication, consult with your veterinarian before using Revolution with any other medications, including vitamins and supplements, since interactions may occur. Where is more information available? Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the Patient Information Sheet on this medication. For technical assistance or to report suspected adverse reactions, call the manufacturer, Pfizer, at 1-800-366-5288.
Revolution works by penetrating the skin and entering your pet’s bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal’s blood. Revolution is safe for pregnant and lactating pets.
How does Revolution work? Revolution is used in the prevention, control, and treatment of various parasite infections. The active ingredient is selamectin, which interferes with the parasite’s nervous system. It is an effective heartworm preventive, killing the immature form of the heartworm (Dirofilaria immitis). It kills adult fleas (Ctenocephalides felis) and prevents flea eggs from hatching for one month. It is also used for the treatment and control of ear mites (Otodectes cynotis) and sarcoptic mange (Sarcoptes scabiei). Revolution is effective in controlling tick infestations due to the American dog tick (Dermacentor variabilis). In cats, Revolution also treats and controls roundworm and hookworm infections.